Main directions of scientific activities:

• Development of delivery systems and carriers for nucleic acids and genes based on nanoparticles
• Transport of drugs through the blood-brain barrier
• Transdermal drug transport
• Training of specialists in the development of drugs based on SNT

• Improving the efficiency of the M
• The extension of the spectrum of the M
• Reduction of toxicity
• Reduction of development costs
• Saving time
• Reduction of technology risks

Main directions of scientific activities:

• the construction of mathematical models and algorithms for coarse-grained modeling of protein mobility in studies of the conformational landscape.
• application of methods of molecular docking, molecular dynamics, virtual screening tasks:
• investigation of the mechanisms of activation/inhibition protein of dipeptidyl peptidase-4.
• the study of molecular mechanisms of conformational rearrangements of the protein PPR-gamma upon interaction with different ligands.
• the virtual creation and screening of libraries of small molecules, in particular, the probability of the CA protein inhibitors of HIV-1.
• study of the antiradical activity of ABTS and other bioflavonoids

Priority metabolomic and chemical-toxicological studies:

• personalized drug therapy based on the analysis of the metabolomic profile of the person
• the gathering and assessment of metabolomic profiles
• diagnosis and evaluation of socially significant diseases
• the assessment of the functional state of human organism as markers of nutrient deficiency
• determination of the qualitative and quantitative composition of complex mixtures of biologically active natural compounds
• development test system of fast establishment of narragansett potentially dangerous psychoactive substances
• development of methodologies to establish the fact of falsification of biologically active food additives (BAA)

Priority biopharmaceutical researches:

• development and implementation of normative documents on quality and standards of medicines
• studies on pharmaceutical substances stability
• definition and breakdown of impurities composition in the objects of study
• tests of comparative kinetics of dissolution
• identification of proteins by peptide mapping
• pharmacokinetic studies on evaluation of ADME processes: absorption, distribution, metabolism and excretion
• in vitro and in vivo search and identification of metabolites
• the study of bioequivalence and comparative bioavailability
• researches on interaction of drugs and therapeutic drug monitoring

Joint research programmes with industry partners:

Together with Waters - Clinical mass spectrometry

Main directions of scientific activities:

• search new original M on a database of known targets
• medical chemistry
• mathematical calculation and synthesis of new medicines
• the study of biological activity of developing connections
• identification of markers of disease
• development of new methods of early diagnosis
• the application of a physico-chemical method for studying molecular processes
• improving methods of instrumental Analytics for the analysis of biologically active substances

Joint research programmes with industry partners:

In conjunction with the company Sciex creating databases drugs, narcotic and psychotropic drugs.

Main directions of scientific activities:

• the conduct of clinical bioequivalence studies
• clinical research at early phase
• studies involving patients with certain diseases

The department has a bank of volunteers, numbering more than 1000 healthy individuals from 18 to 45 years.

The center conducts research in cooperation with leading Russian and foreign pharmaceutical companies

Development of finished dosage forms of drugs

On the basis of the Federal scientific center for research and development of immunological products named after M. P. Chumakov, RAS is a leading Russian developer, manufacturer and exporter of immunobiological preparations.

Tasks:

• The formation of competences in the development and production of immunobiological preparations
• Training sessions
• Research work
• Practice (educational, industrial and pre-diploma)
• The master's program
• School of excellence
• Scientific forums

On the basis of the Federal scientific center for research and development of immunological products named after M. P. Chumakov, RAS is a leading Russian developer, manufacturer and exporter of immunobiological preparations.

The first simulation class pharmaceutical orientation in Sechenovskiy University

Tasks:

• learning the basics of chromatographic analysis
• training in the development of chromatographic methods
• analysis of pharmaceuticals and biological objects
• Formation of skills of work with hardware and software

Tasks:

• Formation of competences in the field of biotechnology

Tasks:

• Formation of competences in the field of regulatory relations of circulation of medicines and medical devices
• Legal regulation
• State regulation of relations
• Quality management
• The system of state control and supervision activities
• Assessment of health technologies
• State policy in the field of drug provision for certain categories of citizens