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Institute for Regenerative Medicine

Explore and expand the possibilities of the human body: from cell therapy to creation of artificial organs using 3D-bioprinting.

The use of stem cells to treat disease (cell therapy)
3D-bioprinting: creating of bioequivalent of organs and tissues by the method of 3D printing living cells
Development of innovative biomaterials for tissue engineering and reconstructive plastic surgery
Researches of biomechanics: measurement of mechanical properties of biological and synthetic materials

Two sides of the same Institute: equally important

Department of advanced cell technologies

Researches of the peculiarities of neurodegenerative diseases (genetics)

We study the role of TRP and ASIC channels in the development of such neurodegenerative diseases as Parkinson's and Alzheimer's diseases. Fundamental mechanisms of pathogenesis of these diseases involving these channels are being investigated. Also, a search for compounds that are able to modulate their work and to influence the rate of progression of neurodegeneration.

The Department of modern biomaterials

The analysis of the chemical composition of the analyzed materials, maps construction of substances distribution in the sample

Spectral analysis of the chemical composition in the infrared range. Determination of composition of organic substances on functional groups. The distribution of substances in the sample with a resolution of 10 µm.

Determination of surface properties of materials

Determination of values of physical quantities characterizing the surface properties of the material.

Bioprinting

Laser transfer for cell cultures and microbial systems at the substrate/scaffold.

The study of micromechanical properties of materials

Determination of Young's modulus of samples of different nature. Mapping the distribution of Young's modulus on the surface of samples.

Sorting of cells

Immunophenotyping of cell cultures. The selection of subpopulations of cells. Selection of single cells for molecular analysis and obtain cloned cell cultures.

Analysis of cytotoxicity of biomaterials

Determination of cytotoxicity of biomaterials by method of assessing the metabolic activity of cells invitro.

Partnership in the biomedical sector

Our partners are pharmaceutical, biotechnology and other medical companies, which accelerates the process of development.

Many possibilities in collaborations

Among our joint projects we have also pharmaceuticals, and software, and transplantation of organs.

Absolutely unique equipment

Some equipment of the Institute is rare not only in Russia but throughout the world as a whole. It is extremely expensive and new equipment with enormous potential.

Services Institute
for Regenerative Medicine

1

Research, development and implementation of methods of cell therapy (NGS)

Study of the potential of various cell cultures and biomaterials for the treatment of certain pathologies

2

Tissue-engineering technology for the recovery of the soft tissues

The main directions of work of the Department associated with the creation of 3-dimensional polymeric structures for tissue-engineered structures and developments of non-scaffold technologies – cell layers and tissue spheroids for functional recovery of the structure of soft tissues.

3

Development of technology for creating tissue-engineered heart valve

In the Department, work is underway on the production of tissue-engineered aortic valve on the basis of biomaterials using methods of decellularization. This technology will significantly reduce the risk of calcification –the main reason for the replacement of the biological conduit. Extended life will allow to use of a biological prosthesis for patients of all ages.

4

Research, development and implementation of methods of tissue engineering

A series of experiments that show the possibility of creating a tissue-engineered structures with the purpose of correction of pathologies of organs and tissues.

5

Research and experiments with usage of space technology

In this research, there will be launched a bioreactor capable of cultivating mammalian cells, including human, in conditions of weightlessness.

Our current projects

A tissue-engineered trachea

The creation of tissue-engineered trachea by using chondrocyte.

A joint project with the University Hospital of Basel

Space bioreactor

The elucidation of the culture conditions of MSC and cell cultures in low gravity.

Project for organization of Roscosmos.

Tissue-engineered bile duct

Creating fragments in bile duct methods of tissue engineering.

Department of advanced cell technologies.

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Тимашев Петр Сергеевич
Timashev Peter
The Director of the Institute for Regenerative Medicine
“
We work with the smartest people in the country in the field of medicine

The number of specialists in the sphere of Russian regenerative medicine will not exceed a hundred people. Therefore, every employee of the Institute is our golden unique with very valuable knowledge.

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